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Dr. Chengguo Xing’s kava clinical study makes the cover of Cancer Prevention Research

Kava’s reputation in preventing cancer just received a boost from the American Association for Cancer Research. The May cover of the organization’s flagship journal, Cancer Prevention Research, featured a clinical study on kava led by Chengguo “Chris” Xing, Ph.D., a professor of medicinal chemistry and the Frank A. Duckworth Eminent Scholar Chair in the UF College of Pharmacy and a member of the UF Health Cancer Center.

Cancer Prevention Research May cover
Cancer Prevention Research’s May cover depicts a kava plant and the major kava-specific lactones responsible for its dual benefits among smokers.

In the pilot clinical trial, Xing and his colleagues evaluated the effects of a seven-day course of kava capsules on tobacco carcinogen metabolism and tobacco usage in active smokers. The results from the study suggest that kava’s twofold cancer prevention mechanism reduces the toxicity of a certain carcinogenic metabolite and relaxes the user, which reduces tobacco cravings.

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Xing first began studying kava in 2005, after epidemiology studies showed an association between consumption of kava and low rates of lung cancer in the South Pacific Islands.